Alpha-arbutin is a glycosylated hydroquinone that is an anomer of naturally occurring arbutin, it can inhibit the enzyme tyrosinase, which is crucial in melanin production. It is a synthetic material produced via enzymatic glycosylation of hydroquinone and is structurally the α-anomer of arbutin.
CAS No.: 84380-01-8
Synonyms: Hydroquinone α-glucoside; Hydroquinone O-α-D-glucopyranoside; 4′-Hydroxyphenyl α-glucoside; 4-Hydroxyphenyl α-glucopyranoside; Hydroquinone-O-α-d-glucopyranoside; 4-Hydroxyphenyl α- d-gluco-hexopyranoside
| Physical Properties | |
| Chemical formula | C12H16O7 |
| IUPAC Name | (2R,3S,4S,5R,6R)-2-(hydroxymethyl)-6-(4-hydroxyphenoxy)oxane-3,4,5-triol |
| Molecular weight | 272.25g/mol |
| Solubility | Water & Alcohol |
| pH | 5.0-7.0 |
| Density | 1.556±0.06 g/cm3 |
| Chemical Properties | |
| Color | White to Off-White |
| State | Solid or Crystalline Powder |
| Melting point | 195-196°C |
| pKa | 10.10±0.15 |
| Loss on Drying | < 0.50% |
| Pictograms : |  |
| Hazard Statements : | H302: Harmful if swallowed |
| Precautionary statements : | P264: Wash thoroughly after handling. P270: Do not eat, drink or smoke when using this product. P301: If swallowed immediately call a POISON CENTER if you feel unwell. P317: Get emergency medical help. P330: Rinse mouth. P501: Dispose of contents/container to an approved waste disposal plant. |
Alpha-arbutin is a glycosylated hydroquinone that is an anomer of naturally occurring arbutin, it can inhibit the enzyme tyrosinase, which is crucial in melanin production. It is a synthetic material produced via enzymatic glycosylation of hydroquinone and is structurally the α-anomer of arbutin.
CAS No.: 84380-01-8
Synonyms: Hydroquinone α-glucoside; Hydroquinone O-α-D-glucopyranoside; 4′-Hydroxyphenyl α-glucoside; 4-Hydroxyphenyl α-glucopyranoside; Hydroquinone-O-α-d-glucopyranoside; 4-Hydroxyphenyl α- d-gluco-hexopyranoside
| Physical Properties | |
| Chemical formula | C12H16O7 |
| IUPAC Name | (2R,3S,4S,5R,6R)-2-(hydroxymethyl)-6-(4-hydroxyphenoxy)oxane-3,4,5-triol |
| Molecular weight | 272.25g/mol |
| Solubility | Water & Alcohol |
| pH | 5.0-7.0 |
| Density | 1.556±0.06 g/cm3 |
| Chemical Properties | |
| Color | White to Off-White |
| State | Solid or Crystalline Powder |
| Melting point | 195-196°C |
| pKa | 10.10±0.15 |
| Loss on Drying | < 0.50% |
| Pictograms : | |
| Hazard Statements : | H302: Harmful if swallowed |
| Precautionary statements : | P264: Wash thoroughly after handling. P270: Do not eat, drink or smoke when using this product. P301: If swallowed immediately call a POISON CENTER if you feel unwell. P317: Get emergency medical help. P330: Rinse mouth. P501: Dispose of contents/container to an approved waste disposal plant. |
Alpha Arbutin is a natural compound derived from the bearberry plant. It’s a popular ingredient in skincare products due to its ability to lighten skin tone and reduce hyperpigmentation.
Alpha Arbutin works by restraining tyrosinase, an enzyme responsible for melanin production. Decreasing melanin production helps to lighten dark spots, freckles, and uneven skin.
Alpha arbutin is a natural compound that lightens dark spots and uneven skin tone by inhibiting melanin production. It can be used with retinol for a more comprehensive skincare routine.
