Climbazole is a constituent of monochlorobenzenes, a member of imidazoles, an aromatic ether, a ketone, and a hemiaminal ether. Broadly utilized in several skincare and haircare products, it is used as a topical medication for treating and preventing fungal infections, especially those infecting the skin and scalp.
CAS No.: 38083-17-9
Synonyms: Climbazole; Baypival; Climbazol; Crinipan AD; Climbazolum
| Physical Properties | |
| Chemical formula | C15H17ClN2O2 |
| IUPAC Name | Climbazole; Baypival; Climbazol; Crinipan AD; Climbazolum |
| Molecular weight | 292.76 g/mol |
| Solubility | DMSO & Ethanol |
| Insoluble | Water |
| Density | 1.1 at 20℃ |
| Chemical Properties | |
| Color | White to Off-white |
| State | Solid powder |
| Melting point | 94.0 to 98.0°C |
| pKa | 5.9-7.4 at 20 ℃ |
| Vapor pressure | 0-0Pa at 20-25℃ |
| pH | 8.5-10.0 (1% in water 20°C) |
| Pictograms : |
|
| Hazard Statements : | H302: Harmful if swallowed. |
| Precautionary statements : | P264: Wash thoroughly after handling. |
Climbazole is a constituent of monochlorobenzenes, a member of imidazoles, an aromatic ether, a ketone, and a hemiaminal ether. Broadly utilized in several skincare and haircare products, it is used as a topical medication for treating and preventing fungal infections, especially those infecting the skin and scalp.
CAS No.: 38083-17-9
Synonyms: Climbazole; Baypival; Climbazol; Crinipan AD; Climbazolum
| Physical Properties | |
| Chemical formula | C15H17ClN2O2 |
| IUPAC Name | Climbazole; Baypival; Climbazol; Crinipan AD; Climbazolum |
| Molecular weight | 292.76 g/mol |
| Solubility | DMSO & Ethanol |
| Insoluble | Water |
| Density | 1.1 at 20℃ |
| Chemical Properties | |
| Color | White to Off-white |
| State | Solid powder |
| Melting point | 94.0 to 98.0°C |
| pKa | 5.9-7.4 at 20 ℃ |
| Vapor pressure | 0-0Pa at 20-25℃ |
| pH | 8.5-10.0 (1% in water 20°C) |
| Pictograms : |
|
| Hazard Statements : | H302: Harmful if swallowed. |
| Precautionary statements : | P264: Wash thoroughly after handling. |
Climbazole is a key ingredient in many anti-dandruff shampoos. It works by effectively reducing dandruff and scalp irritation caused by Malassezia fungi. Additionally, by promoting a healthy scalp environment, it can indirectly contribute to hair growth.
Both ketoconazole and climbazole are effective antifungal agents used to treat dandruff. Ketoconazole is generally more potent, while climbazole is milder and suitable for sensitive scalps. Consult a dermatologist to determine the best option for your specific needs.
Yes, climbazole is generally considered safe for most people when used as directed. It’s a
well-tolerated ingredient and rarely causes side effects. However, as with any product, it’s advisable to do a patch test before using it on a larger area of your scalp. If you experience any adverse reactions, discontinue use and consult a dermatologist.
