Acetamide is an inorganic compound derived from acetic acid. Its structure can be considered an intermediate between acetone and urea. It also occurs naturally as a mineral or can be produced in the laboratory via the dehydration of acetonitrile. Moreover, it has also been detected in space near the center of the Milky Way galaxy and on comet 67P during the Philae lander mission.
CAS No.: 60-35-5
Synonyms: Ethanamide; Acetic acid amide; Methanecarboxamide; Acetimidic acid; Ethanimidic acid.
| Physical Properties | |
| Chemical formula | CH3CONH2 |
| IUPAC Name | acetamide |
| Molecular weight | 59.07 g/mol |
| Solubility | Water & Ethanol |
| Density | 1.585 g/cm³ |
| Flash point | 126 °C |
| Chemical Properties | |
| Color | Colorless |
| State | Solid Crystals |
| Melting point | 79 – 81 °C |
| Log P | −1.26 |
| pKa | 15.1 (at 25 °C) |
| Pictograms : |  |
| Hazard Statements : | H351: Suspected of causing cancer. |
| Precautionary statements : | P201: Obtain special instructions before use. P202: Do not handle until all safety precautions have been read and understood. P280: Wear protective gloves/ protective clothing/ eye protection/ face protection. P308 + P313: IF exposed or concerned: Get medical advice/ attention. P405: Store locked up. P501: Dispose of contents/ container to an approved waste disposal plant. |
Acetamide is an inorganic compound derived from acetic acid. Its structure can be considered an intermediate between acetone and urea. It also occurs naturally as a mineral or can be produced in the laboratory via the dehydration of acetonitrile. Moreover, it has also been detected in space near the center of the Milky Way galaxy and on comet 67P during the Philae lander mission.
CAS No.: 60-35-5
Synonyms: Ethanamide; Acetic acid amide; Methanecarboxamide; Acetimidic acid; Ethanimidic acid.
| Physical Properties | |
| Chemical formula | CH3CONH2 |
| IUPAC Name | acetamide |
| Molecular weight | 59.07 g/mol |
| Solubility | Water & Ethanol |
| Density | 1.585 g/cm³ |
| Flash point | 126 °C |
| Chemical Properties | |
| Color | Colorless |
| State | Solid Crystals |
| Melting point | 79 – 81 °C |
| Log P | −1.26 |
| pKa | 15.1 (at 25 °C) |
| Pictograms : | |
| Hazard Statements : | H351: Suspected of causing cancer. |
| Precautionary statements : | P201: Obtain special instructions before use. P202: Do not handle until all safety precautions have been read and understood. P280: Wear protective gloves/ protective clothing/ eye protection/ face protection. P308 + P313: IF exposed or concerned: Get medical advice/ attention. P405: Store locked up. P501: Dispose of contents/ container to an approved waste disposal plant. |
Yes, acetamide can form hydrogen bonds due to the presence of both a carbonyl group (C=O) and an amide group (NH2).
Acetamide is polar due to its amide group, which consists of a polar carbonyl (C=O) and amine (NH2) group, leading to an uneven dispersal of charges.
Acetamide is employed as a solvent in various industrial processes, a plasticizer for polymers, and an intermediate in the synthesis of pharmaceuticals, pesticides, and other organic compounds.
Acetamide is usually considered neutral, but it can exhibit weak acidic behavior due to the presence of the amide group (–CONH2). However, it is not strongly acidic and does not behave like typical acids.
Acetamide usually serves as a solvent and a chemical intermediate. It assists in organic synthesis and electrochemical processes due to its high dielectric constant.
